MULTIPLE INTRAVENOUS INFUSIONS OF VEPOLOXAMER (PURIFIED POLOXAMER −188) ELICIT PROGRESSIVE IMPROVEMENTS IN PLASMA BIOMARKERS IN DOGS WITH ADVANCED HEART FAILURE
نویسندگان
چکیده
منابع مشابه
Systemic inflammation in dogs with advanced-stage heart failure
BACKGROUND Although human studies have shown that inflammation plays a role in the development of congestive heart failure, scarce information exists on white blood cell count (WBC) and differential cell counts in various stages of heart failure in man and dogs. A few studies demonstrated increased concentrations of C-reactive protein (CRP), a major acute-phase protein, in cardiac diseases in d...
متن کاملDifferential Effects of Commercial-Grade and Purified Poloxamer 188 on Renal Function
Poloxamer 188 (P188) is a non-ionic amphiphilic copolymer with hemorheologic, antithrombotic, anti-inflammatory, and cytoprotective properties. It potentially has clinical utility in diverse diseases, such as acute myocardial infarction, acute limb ischemia, shock, acute stroke, heart failure, and sickle cell crisis. P188 is available as an excipient-grade product, manufactured to National Form...
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Background: Heart failure is one of the most common cardiovascular disorders and is considered a chronic, progressive and debilitating disorder. The medical treatment of this disease is accompanied by many problems. Today, stem cells are being used increasingly to reduce the problems of heart failure treatments. Since pro-inflammatory cytokines play an important role in the prognosis and progre...
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Nowadays, heart failure (HF) has an increasing prevalence, particularly in the elderly, and is becoming a clinical problem of epidemic proportion in terms of morbidity and mortality. Developing biological markers, that can aid in the diagnosis of HF and in the differentiation of congestive heart failure (CHF) from other causes of dyspnoea, will reduce the cost of health care. However, an ideal ...
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http://heart.bmj.com/content/96/4/314.full.html Updated information and services can be found at: These include: References http://heart.bmj.com/content/96/4/314.full.html#ref-list-1 This article cites 23 articles, 14 of which can be accessed free at: service Email alerting box at the top right corner of the online article. Receive free email alerts when new articles cite this article. Sign up ...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2016
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(16)31552-2